Representation and matching of knowledge to design digital systems

A knowledge-based expert system is described that provides an approach to solve a problem requiring an expert with considerable domain expertise and facts about available digital hardware building blocks. To design digital hardware systems from their high level VHDL (Very High Speed Integrated Circuit Hardware Description Language) representation to their finished form, a special data representation is required. This data representation as well as the functioning of the overall system is described

Cryogenic propellant venting under low pressure conditions Final report

Wall temperatures and heat transfer coefficients for solid-vapor mixtures of para hydrogen and nitrogen venting under low pressur

Ecological Modeling of Aedes aegypti (L.) Pupal Production in Rural Kamphaeng Phet, Thailand

Background - Aedes aegypti (L.) is the primary vector of dengue, the most important arboviral infection globally. Until an effective vaccine is licensed and rigorously administered, Ae. aegypti control remains the principal tool in preventing and curtailing dengue transmission. Accurate predictions of vector populations are required to assess control methods and develop effective population reduction strategies. Ae. aegypti develops primarily in artificial water holding containers. Release recapture studies indicate that most adult Ae. aegypti do not disperse over long distances. We expect, therefore, that containers in an area of high development site density are more likely to be oviposition sites and to be more frequently used as oviposition sites than containers that are relatively isolated from other development sites. After accounting for individual container characteristics, containers more frequently used as oviposition sites are likely to produce adult mosquitoes consistently and at a higher rate. To this point, most studies of Ae. aegypti populations ignore the spatial density of larval development sites. Methodology - Pupal surveys were carried out from 2004 to 2007 in rural Kamphaeng Phet, Thailand. In total, 84,840 samples of water holding containers were used to estimate model parameters. Regression modeling was used to assess the effect of larval development site density, access to piped water, and seasonal variation on container productivity. A varying-coefficients model was employed to account for the large differences in productivity between container types. A two-part modeling structure, called a hurdle model, accounts for the large number of zeroes and overdispersion present in pupal population counts. Findings - The number of suitable larval development sites and their density in the environment were the primary determinants of the distribution and abundance of Ae. aegypti pupae. The productivity of most container types increased significantly as habitat density increased. An ecological approach, accounting for development site density, is appropriate for predicting Ae. aegypti population levels and developing efficient vector control program

A Puzzling Merger in A3266: the Hydrodynamic Picture from XMM-Newton

Using the mosaic of nine XMM-Newton observations, we study the hydrodynamic state of the merging cluster of galaxies Abell 3266. The high quality of the spectroscopic data and large field of view of XMM-Netwon allow us to determine the thermodynamic conditions of the intracluster medium on scales of order of 50 kpc. A high quality entropy map reveals the presence of an extended region of low entropy gas, running from the primary cluster core toward the northeast along the nominal merger axis. The mass of the low entropy gas amounts to approximately 2e13 solar masses, which is comparable to the baryonic mass of the core of a rich cluster. We test the possibility that the origin of the observed low entropy gas is either related to the disruption a preexisting cooling core in Abell 3266 or to the stripping of gas from an infalling subcluster companion. We find that both the radial pressure and entropy profiles as well as the iron abundance of Abell 3266 do not resemble those in other known cooling core clusters (Abell 478). Thus we conclude that the low entropy region is subcluster gas in the process of being stripped off from its dark matter halo. In this scenario the subcluster would be falling onto the core of A3266 from the foreground. This would also help interpret the observed high velocity dispersion of the galaxies in the cluster center, provided that the mass of the subcluster is at most a tenth of the mass of the main cluster.Comment: 6 pages, ApJ sub

Higgs boson pair production in gluon fusion at NLO with full top-quark mass dependence

We present the calculation of the cross section and invariant mass distribution for Higgs boson pair production in gluon fusion at next-to-leading order (NLO) in QCD. Top-quark masses are fully taken into account throughout the calculation. The virtual two-loop amplitude has been generated using an extension of the program GoSam supplemented with an interface to Reduze for the integral reduction. The occurring integrals have been calculated numerically using the program SecDec. Our results, including the full top-quark mass dependence for the first time, allow us to assess the validity of various approximations proposed in the literature, which we also recalculate. We find substantial deviations between the NLO result and the different approximations, which emphasizes the importance of including the full top-quark mass dependence at NLO.Comment: Version published in PRL, v2: results at 13 TeV (v1 was at 14 TeV), minor correction to virtual part included, conclusions unchange

Randomised field trial to evaluate serological response after foot-and-mouth disease vaccination in Turkey

AbstractDespite years of biannual mass vaccination of cattle, foot-and-mouth disease (FMD) remains uncontrolled in Anatolian Turkey. To evaluate protection after mass vaccination we measured post-vaccination antibodies in a cohort of cattle (serotypes O, A and Asia-1). To obtain results reflecting typical field protection, participants were randomly sampled from across Central and Western Turkey after routine vaccination. Giving two-doses one month apart is recommended when cattle are first vaccinated against FMD. However, due to cost and logistics, this is not routinely performed in Turkey, and elsewhere. Nested within the cohort, we conducted a randomised trial comparing post-vaccination antibodies after a single-dose versus a two-dose primary vaccination course.Four to five months after vaccination, only a third of single-vaccinated cattle had antibody levels above a threshold associated with protection. A third never reached this threshold, even at peak response one month after vaccination. It was not until animals had received three vaccine doses in their lifetime, vaccinating every six months, that most (64% to 86% depending on serotype) maintained antibody levels above this threshold. By this time cattle would be >20 months old with almost half the population below this age. Consequently, many vaccinated animals will be unprotected for much of the year. Compared to a single-dose, a primary vaccination course of two-doses greatly improved the level and duration of immunity. We concluded that the FMD vaccination programme in Anatolian Turkey did not produce the high levels of immunity required. Higher potency vaccines are now used throughout Turkey, with a two-dose primary course in certain areas.Monitoring post-vaccination serology is an important component of evaluation for FMD vaccination programmes. However, consideration must be given to which antigens are present in the test, the vaccine and the field virus. Differences between these antigens affect the relationship between antibody titre and protection

Trigonometric R Matrices related to `Dilute' Birman--Wenzl--Murakami Algebra

Explicit expressions for three series of $R$ matrices which are related to a ``dilute'' generalisation of the Birman--Wenzl--Murakami are presented. Of those, one series is equivalent to the quantum $R$ matrices of the $D^{(2)}_{n+1}$ generalised Toda systems whereas the remaining two series appear to be new.Comment: 5 page